Aphantix Frusemide Tablets

(Frusemide Tablets BP 40 mg)

For use of Registered medical Practitioner or a Hospital or a Laboratory only.



Each Uncoated Tablet Contains:

Frusemide BP 40 mg



Aphantix is indicated in adults, infants, and children for the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome. Frusemide is particularly useful when an agent with greater diuretic potential is desired. Frusemide may be used in adults for the treatment of hypertension alone or in combination with other antihypertensive agents.

Hypertensive patients who cannot be adequately controlled with thiazides will probably also not be adequately controlled with frusemide alone.



Aphantix is contraindicated in patients with anuria and in patients with a history of hypersensitivity to frusemide.



Route: oral

Hypertension: 40 mg to 80 mg oral dose/BD.

Oedema: 20 mg to 80mg as single dose.



Patients receiving Frusemide should be advised that they may experience symptoms from excessive and/or electrolyte losses. The postural hypotension that sometimes occurs can usually be managed by getting up slowly. Potassium supplements and/or dietary measures may be needed to control or avoid hypokalemia.

Patients with diabetes mellitus should be told that Frusemide may increase blood glucose levels and thereby urine glucose tests. The skin of some patients may be more sensitive to the effects of sunlight while taking Frusemide.



Hypokalaemia, acute saline depletion, dilutional hyponatraemia, gastrointestinal disturbance, magnesium depletion, dizziness, lethargy. Noise in the ears (high dose), muscle craps, rash, ototoxicity.



Frusemide may increase the ototoxic potential of aminoglycoside antibiotics, ‘when: used concomitantly.

Patients receiving high doses of salicylates concomitantly with Frusemide, may experience salicylate toxicity at lower doses. Frusemide can antagonize the skeletal muscle relaxing effects of tubocurarine and may potentiate the action of succinylcholine.
Frusemide may add to or potentiate the therapeutic effect of other antihypertensive drugs. Petentiation occurs with ganglionic or peripheral adrenergic blocking drugs.

Frusemide may decrease arterial responsiveness to. However, norepinephrine may still be used effectively. Simultaneous administration of sucralfate and Frusemide tablets may reduce the natriuretic and antihypertensive effects of Frusemide. Patients receiving both drugs should be observed closely to determine if the desired diuretic and/or antihypertensive effect of Frusemide is achieved. The intake of Frusemide and sucralfate should be separated by at least two hours.



Store in a cool place and protect from light.

Keep all medicines out of reach of children.



Pack of 25 Strips of 10 Tablets in a carton and Pack of 1000 tablets in ajar.


Mfg. Lic. No: KD-493

Nafdac Reg. No.: 04-9146


Manufactured by


Plot No. 59, 60, 85, 86. V.M.I.E, Dowali Village,

Vasal (W), Dist. Thane, Maharashtra, India.



Sole Agent

Aphantee Pharma Nig. Ltd.

13A, Old Cemetary Road, Onitsha,

Anambara State, Nigeria.

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