Astymin Crystalline Essential Amino Acids and Multivitamin Capsules

ASTYMIN

CRYSTALLINE ESSENTIAL AMINO ACIDS AND MULTIVITAMIN CAPSULES


Astymin capsules contain all the essential AMINO ACIDS, Vitamins and Minerals. AMINO ACIDS used in Astymin are pure crystalline, in known quantities.

Astymin which contains 20 ingredients is manufactured by Marumerization technology to ensure stability and uniformity. Marumerization ensures uniform dissolution and avoids drug dumping.

Each capsule contains:
Essential Amino Acids
L-leucine USP 18.3 mg – L-isoleucine USP 5.9 mg – L-lysine hydrochloride USP 25.0mg – L-phenylalanine USP 5.0 mg – L-threonine USP 4.2 mg – L-valine USP 6.7 mg – L-tryptophan USP 5.0 mg – DL-methionine USP XXI 18.4 mg

Vitamins
Vitamin A (as synthetic retinol concentrate powder form) BP 2500 I.U. – Colecalciferol BP 200 I.U -Thiamine nitrate BP 5.0 mg – Riboflavin BP 3.0 mg – Nicotinamide BP 25.0 mg – Pyridoxine hydrochloride BP 1.5 mg -Folic acid BP 0.75 mg – Calcium pantothenate BP 5.0mg – Cyanocobalamin BP 2.5 mcg – Ascorbic acid BP 40.0 mg – Alpha tocopheryl acetate BP 7.5 I.U.

Colours used: Indigo carmine, Sunset yellow FCF, Carmoisine and Titanium Dioxide.

 

PHARMACOLOGICAL ACTION

Amino acids are the basic building blocks of proteins and enzymes and are essential for normal healthy bodily function especially during growth and convalescence. The essential amino acids cannot be made in the body and must be included in the diet or as a supplement.

Vitamins B1, B2, B6 and nicotinamide form parts of co-enzyme systems concerned with release of energy from foodstuffs. Like the essential amino acids and minerals, they cannot be made in the body and must be included in the diet in small quantities. The B-complex vitamins are water-soluble and are not stored in the body in appreciable amounts. Consequently regular replenishment of these vitamins is required. Their presence prevents the development of certain deficiency diseases such as beri-beri, riboflavinosis and pellagra.

 

INDICATIONS

Astymin capsules are indicated in the treatment of patients with deficiencies of or increased requirements of AMINO ACIDS and vitamins in

Malnutrition            As an adjunct to
Stress                         – Antibiotics
Convalescence        – Hypoglycemic Drugs
DebiIity                     – Anti Hypertensives
Alcoholism               – Anti TB drugs
Following Injury

 

DOSAGE AND DIRECTIONS FOR USE

One capsule twice a day, or as directed by the physician. Do not exceed recommended dose.

 

CONTRA-INDICATIONS

Hypersensitivity to any of the ingredients. Pantothenol is contra-indicated in haemophiliacs and in patients with ileus due to mechanical obstruction.

 

PREGNANCY & LACTATION

Excessive doses of Vitamin A should be avoided in pregnancy because of potential teratogenic effects. Lactating women should not take vitamin D if possible, as this may lead to the development of hypercaIcaemia in the infant.

 

DRUG INTERACTION

Vitamin A: Absorption of vitamin A from the gastro-intestinal tract may be reduced by the presence of neomycin, cholestyramine, or liquid paraffin; absorption may also be impaired in cholestatic jaundice and fat-malabsorption conditions.

Vitamin B6: Reduces the effects of levodopa.

Vitamin D: The effects of Vitamin D may be reduced in patients taking barbiturates or anticonvulsants.

 

SIDE EFFECTS

Vitamin C: Large doses may cause diarrhoea and other gastro-intestinal disturbances and are associated with the formation of renal calcium oxalate calculi. Vitamin C should be given with care to patients with hyperoxaluria. Tolerance may be induced with prolonged use of large doses.

Vitamin D: Should not be administered to patients with hypercalcaemia, and be given with caution to infants, as they may have increased sensitivity to its effects.

 

KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT

Vitamin A: Excessive amounts over long periods can lead to toxicity, known as hypervitaminosis A, characterised by fatigue, irritability and loss of weight, vomiting and other gastro-intestinal disturbances, low-grade fever, hepatosplenomegaly, skin changes, alopecia, dry hair, cracking and bleeding lips, anaemia headache, hypercalcaemia, subcutaneous swelling, and pains in bones and joints. Symptoms of chronic toxicity in children may also include raised intracranial pressure and papilloedema mimicking brain tumours, tinnitus visual disturbances which may be severe, and painful swelling over the long bones. Symptoms usually clear on withdrawal of vitamin A, but in children premature close of the epiphyses of the long bones may result in arrested bone growth. Acute vitamin A intoxication may occur with very high doses and is characterised by sedation, dizziness, nausea and vomiting, erythema, pruritus and desquamation.

Vitamin B6: Long-term administration of large doses of pyridoxine is associated with the development of severe peripheral neuropathies.

Vitamin D: Excessive intake of vitamin D leads to the development of hypercalcaemia which is characterised by anorexia, nausea, vomiting, constipation, abdominal pain, muscle weakness, mental disturbances, polydipsia, polyuria, bone pain, nephrocalcinosis, renal calculi, and in severe cases cardiac arrhythmias and coma.

 

PRESENTATION

Blister pack of 2 x 10 capsules with individual carton.

 

STORAGE

Store below 30°C. Protect from direct sunlight.
“KEEP ALL MEDICINES OUT OF REACH AND SIGHT OF YOUNG CHILDREN”

 

Imported and Marketed by

Fidson Healthcare Plc

268 Ikorodu Road, Obanikoro, Lagos, Nigeria

 

Made in India by

TIL HEALTHCARE PVT. LTD.

100, Sri city SEZ, Irugulam Post,

Andhra Pradesh – 517 588, India.

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