Chaztfed Chlorpheniramine Maleate BP Tablet

Chlorpheniramine maleate BP



Chaztfed Tablets: Round, flat white tablets each containing chlorpheniramine maleate BP 4mg with CHAZTFED engraved round the perimeter of one side.



Chaztfed tablets are indicated for symptomatic control of all allergic conditions responsive to antihistamines, including hayfever, vasomotor rhinitis, urticaria, angioneurotic oedema, food allergic, drug and serum reaction, insect bites.


Dosage and Administration

The doses below are to be taken three to four times daily or as directed by your physician.

Adults: One tablet.

Children (6-12 years): Half to one tablet depending on age and weight.



Chaztfed is contra-indicated in patients who are hypertensive to antihistamines and those that have had MAOI (monoamine oxidase inhibitor) therapy within the previous 14 days.



Chlorpheniramine may have an additive effect when used concurrently with hynotics and anxiolytics causing potentiation of drowsiness.

A similar additive effect will result from concurrent usage of alcohol with chlorpheniramine.

Monoamine oxidase inhibitor therapy intensifies the anticholinergic effects of Chlorpheniramine. Chlorpheniramine inhibits phenytoin metabolism and can lead to
phenytoin toxicity. The anticholinergic properties of Chlorpheniramine may cause drowsiness, dizziness, blurred vision and psychomotor impairment, which can seriously hamper the patient’s ability to drive and use machinery.

Chaztfed should only be used during pregnancy when clearly needed and when potential benefit outweighs the potential risks to the foetus.


Side- Effects

Sedation varying from slight drowsiness to deep sleep, inability to concentrate, lassitude, blurred vision, gastrointestinal disturbances such as nausea, vomiting and diarrhea may occasionally occur. Urinary retention, headaches, dryness of the mouth, dizziness, palpitation, tachycardia arrhythmias, hypertension, tightness of the chest, abdominal pain infrequently occur.

Allergic reactions including exfoliative dermatitis, photosensitivity and skin reaction, urticaria, twitching, muscular weakness and incoordination. Tinnitus, depression, irritablity and nightmares, infrequently occur.

Paradoxcal excitation in children and confusional psychosis in the elderly can occur. The effects of alcohol may be increased, in common with other drugs having anticholinergic effects, chlorpheniramine should be used with caution in epilepsy, prostatic hypertrophy, glaucoma, hepatic disease thyrotoxicosis, raised intra-ocular pressure, severe hypertension or cardiovascular disease. Children and the elderly are more likely to experience the neurological anticholinergic effects.



The estimated lethal dose of chaztfed is 25-50mg/kg body weight. Symptoms and signs include sedation, paradoxical stimulation of CNS, toxic psychosis, seizures, apnoea, anticholinergic effects dystonic reactions and cardiovascular collapse.

Treatment includes gastric lavage or emsis using tablet of Ipecacuanha. Following these measures, activated charcoal and cathartics may be administered to minimise absorption. If overdosage is by the oral route, other symptomatic and supportive measures should be provided with special attention to cardiac, respiratory, renal and hepatic functions and fluid and electrolytes balance.

Treat hypertension and arrhythmias vigorously. CNS convulsions may be treated with IV Diazepam or phenytoin. Haemoperfusion may be used in severe cases.



Chaztfed tablet: 10 strips of 10 tablet.



Chaztfed preparation should be stored below 25oC and protected from light.



Keep all medicines out of the reach of children.


Manufactured by

Chazmax Pharmaceutical Industries Ltd.

Odume Layout, Off Km2 Nkpor/Obosi Road,

Obosi, Anambra State, Nigeria.

Published by


I am a blogging and data enthusiast.