Cikaclox® Ampicillin and Cloxacillin Broad Spectrum Antibiotic
Introduction, Absorption and excretion, Indications, Side effects, Dosage and administration, Preparation of the suspension, Storage, Contraindications, Precautions, Composition, Availability and Manufacturer of Cikaclox Capsule, Suspension Medicine for Infections.
Cikaclox is a composition of Ampicillin Trihydrate (125mg base) and Pencillinase resistant Cloxadilllin sodium (125mg base), which is a wide spectrum antibiotic effective against a range of Gram positive and Gram negative organisms.
ABSORPOTION AND EXCRETION
Cikaclox is acid stable and well absorbed orally giving peak serum levels about 2 hrs after dosing. It is excreted primarily by the kidney through glomerular filtration and tubular secretion.
Cikaclox is effective in the treatment of the following bacterial infections:
– Respiratory Tract Infections (Upper and Lower)
– Ear, Nose and Throat infections
– Bone and joints infections
– Pelvic infections
– Gastro-intestinal infections
– Urinary Tract infections
– Septicaemia, Endocarditis and Orthopaedic infections.
Diarrhoea, Nausea and hearthum. Allergic reactions, skin rashes, interstitial nepritis and Vasculitis.
DOSAGE AND ADMINISTRATION
Administer half hour before meals
Syrup: Children: 1 month-2years: one teaspoonful 4 times daily 2-10 years: two teaspoonfuls 4 times daily
Drop: 0.6ml: 4 times daily or as directed by physician
Capsule: One capsule:4 times daily or as directed by physician
PREPARATION OF THE SUSPENSION
To make 100ml of the suspension, add 72.5ml of boiled and cooled water, invert and shake the bottle until all powder is dispersed.
SHAKE WELL BEFORE EACH DOSE
The dry powder should be stored below 25°C. The suspension should be used within 7 days of preparation and stored in a cool place preferably in a refrigerator.
Reduced dosage is required in patients with impaired renal functions e.g. renal failure; Neonates and premature infants.
COMPOSITION AND AVAILABILITY
SUSPENSION: 250mg powder syrup. When reconstituted each 5ml contains 125mg ampicillin as the trihydrate BP plus 125mg Cloxacillin as the sodium salt BP. In 100ml bottle
CAPSULES: 500mg: 250mg ampicillin as Ampicillin Trihydrate BP and 250mg Cloxacillin as Cloxacillin Sodium BP.
Michelle Laboratories Ltd.
Plot 23, Block 2,Thinkers Corner
Industrial Layout, Enugu,
Enugu Sate, Nigeria.