Disogel Chewable Tablets and Suspension

DISOGEL

 

Composition

TABLET

Each chewable tablet contains:

Deglycyrrhizinated Liquorice
equivalent to Liquorice B.P. 400 mg.

Dried Aluminium Hydroxide Gel B.P. 250 mg.

Magnesium Hydroxide B.P. 20 mg.

Simethicone U.S.P. 40 mg.

Colours : Tartrazine, Ponceau 4R, Brilliant Blue FCF.

SUSPENSION

Each 5 ml. contains:

Deglycyrrhizinated Liquorice.
equivalent to Liquorice B.P. 400 mg.

Aluminium Hydroxide Gel Paste
equivalent to Dried Aluminium Hydroxide B.P. 250 mg.

Magnesium Hydroxide Paste
equivalent to Magnesium Hydroxide B.P. 250 mg.

Simethicone U.S.P. 40 mg.

Colour: Tartrazine.

 

Pharmacodynamics

Disogel contains Deglycrrhizinated Liquorice (DGL), which has been known to increase mucus production, increase local tissue blood flow, cause regeneration of mucosa, ulcer healing, etc. It has also been proposed that DGL’s therapeutic benefit may be medicated through increased production of endogenous prostaglandin. Disogel further contains a balanced combination of Aluminum Hydroxide and Magnesium Hydroxide in order to counteract each other’s side effects i.e. constipation and diarrhea respectively.

Simethicone reduces surface tension of gas bubbles; causing them to coalease thus gas is freed and eliminated more easily by belching or passing flatus. Disogel is a well-balanced antacid, which through its unique cytoprotective action controls peptic ulcer disease.

 

Indications

Disogel is indicated in peptic ulcer disease including duodenal Ulcer, gastric ulcer, hyperacidity, dyspepsia, and heartburn in pregnancy, gastritis and flatulence.

 

Dosage and Administration

Tablet: 1 to 2 tablets between meals or as directed by the physician.

Suspension: One to two teaspoonfuls thrice or four times daily or as directed by the physician.

 

Adverse Effects

Side effect with deglycryyhizinated Liquorice has been minimal. Mild diarrhoea has been the most common complaint. However it has been of little consequence, headaches have been reported, usually in patients with a well-documented history of transient headaches. There have been no reports of fluid retention, hypokalemia or drug induced elevation of blood pressure.

 

Availability

Disogel tablets are available in pack of 15 x 10 T strips with Chocolate flavor.

Disogel suspension is available in bottle of 175 ml with Pineapple and Strawberry flavors.

 

Manufactured in India by

Concept Pharmaceuticals Ltd.

A-28/3, MIDC, Chikalthana, Aurangabad-431 006.

Regd. Office: 501, Jaisingh Business Center, 119, Sahar Road,

Andheri (E), Mumbai – 400 099.

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