Ferobin Plus Ferrous Fumarate Vitamins and Folic Acid Capsule

FEROBIN-PLUS CAPSULE

 

COMPOSITION

Each capsule contains:

Ferrous Fumarate BP 300mg

Vitamin B12 BP 10mcg

Folic Acid BP 5mg

 

DESCRIPTION

Ferobin-plus capsule contains Ferrous Fumarate as a source of iron for the treatment of iron-deficiency anaemia. It also contain Folic Acid and Cyanocobalamin (Vitamin B12) which are used in the treatment of megaloblastic anaemia.

 

CLINICAL PHARMACOLOGY

Iron is an integral component of the body, being necessary for heamoglobin formation; haemoglobin is essential in oxygen transport and for the oxidative processes of living tissues. Iron-deficiency results in defective erythropoiesis and anaemia. Iron-deficiency anaemia responds to oral iron therapy.

 

INDICATIONS

Ferobin-plus capsule is indicated for

– Nutritional supplement.

– Iron-deficiency anaemia

– Megaloblastic anaemia

– Anaemia due to pregnancy

– Anaemia due to excessive or repeated hemorrhage

– Anaemia associated with infections and malignant diseases

 

SIDE EFFECTS

Nausea, diarrhea or constipation, abdominal discomfort or pain, gastro intestinal upset and black stools.

 

PRECAUTION

Caution should be exercised in patients with history of peptic ulcer, severe kidney failure and any allergy to any of the constituents.

 

CONTRAINDICATIONS

Hypersensitivity to any of the ingredient.

 

DRUG INTERACTIONS

Iron forms an insoluble complex with several other drugs, resulting in decreased absorption of both iron and the other drugs. Examples include tetracycline, penicillamine, methyldopa, levodopa, bisphosphonates and quinolones. The same can occur with elements in food, such as calcium.

Absorption of iron is better at a low pH (an acid environment) and reabsorption is decreased if there is a simultaneous intake of antacids, phosphates, etc.

 

DOSAGE AND ADMINISTRATION

Adults and Children above 12 years

As nutritional supplement: 1 capsule daily.

During illness, blood loss, general weakness or pregnancy: 1 capsule twice daily.

 

SYMPTOMS OF OVERDOSE AND ANTIDOTE

The absorption of excessive quantities of ingested iron results in systemic iron toxicity.

Severe overdose causes impaired oxidative phosphorylation and mitochondrial dysfunction, which can result in cellular death. The liver is one of the organs most affected by the iron toxicity, but other organs such as the heart, kidneys, lungs, and the hematologic systems may also be impaired. Individuals demonstrate signs of GI toxicity with ingestions of more than 20 mg/kg, but less than or equal to 40 mg/kg.

Acute overdose can be fatal to both children and adults and can occur by both the oral and parenteral route.

Methods for preventing toxicity utilise gastric lavage and chelating agents.

 

PRESENTATION

It is presented as 3 x 10 capsules.

 

STORAGE CONDITIONS

Store below 30°C.

Protect from direct sunlight

 

Manufactured by

Fidson Healthcare Plc.

Km. 38, Lagos – Abeokuta Expressway,

Sango Ota, Ogun State, Nigeria.

customercare@fidson.com

www.fidson.com

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