Each capsule contains:
Ferrous Fumarate BP 300mg
Vitamin B12 BP 10mcg
Folic Acid BP 5mg
Ferobin-plus capsule contains Ferrous Fumarate as a source of iron for the treatment of iron-deficiency anaemia. It also contain Folic Acid and Cyanocobalamin (Vitamin B12) which are used in the treatment of megaloblastic anaemia.
Iron is an integral component of the body, being necessary for heamoglobin formation; haemoglobin is essential in oxygen transport and for the oxidative processes of living tissues. Iron-deficiency results in defective erythropoiesis and anaemia. Iron-deficiency anaemia responds to oral iron therapy.
Ferobin-plus capsule is indicated for
– Nutritional supplement.
– Iron-deficiency anaemia
– Megaloblastic anaemia
– Anaemia due to pregnancy
– Anaemia due to excessive or repeated hemorrhage
– Anaemia associated with infections and malignant diseases
Nausea, diarrhea or constipation, abdominal discomfort or pain, gastro intestinal upset and black stools.
Caution should be exercised in patients with history of peptic ulcer, severe kidney failure and any allergy to any of the constituents.
Hypersensitivity to any of the ingredient.
Iron forms an insoluble complex with several other drugs, resulting in decreased absorption of both iron and the other drugs. Examples include tetracycline, penicillamine, methyldopa, levodopa, bisphosphonates and quinolones. The same can occur with elements in food, such as calcium.
Absorption of iron is better at a low pH (an acid environment) and reabsorption is decreased if there is a simultaneous intake of antacids, phosphates, etc.
DOSAGE AND ADMINISTRATION
Adults and Children above 12 years
As nutritional supplement: 1 capsule daily.
During illness, blood loss, general weakness or pregnancy: 1 capsule twice daily.
SYMPTOMS OF OVERDOSE AND ANTIDOTE
The absorption of excessive quantities of ingested iron results in systemic iron toxicity.
Severe overdose causes impaired oxidative phosphorylation and mitochondrial dysfunction, which can result in cellular death. The liver is one of the organs most affected by the iron toxicity, but other organs such as the heart, kidneys, lungs, and the hematologic systems may also be impaired. Individuals demonstrate signs of GI toxicity with ingestions of more than 20 mg/kg, but less than or equal to 40 mg/kg.
Acute overdose can be fatal to both children and adults and can occur by both the oral and parenteral route.
Methods for preventing toxicity utilise gastric lavage and chelating agents.
It is presented as 3 x 10 capsules.
Store below 30°C.
Protect from direct sunlight
Fidson Healthcare Plc.
Km. 38, Lagos – Abeokuta Expressway,
Sango Ota, Ogun State, Nigeria.