Gloprozole Omeprazole Capsules 20 mg

Dosage form, Composition, Pharmacological effects, Indications, Dosage, Contraindications, Warning and precautions, Side effects and adverse reactions, Drug interactions, Pack, Storage, NAFDAC registration number, Manufacturer and Sole agent of Gloprozole Omeprazole Capsule Medicine for Ulcers.

Dosage Form
Hard Gelatin Capsules

Composition
Each hard gelatin capsule contains:
Omeprazole BP 20mg
(As enteric coated pellets)

Pharmacological effects
It is a gastric proton pump inhibitor. Omeprazole is a substituted benzimidazole derivatives acts on the final step of acid production and therefore controls intragastric acidity irrespective of stimulus. It markedly inhibits basal and stimulated gastic acid secretion. Thus it is antisecretory drug which is very effective for rapidly healing peptic ulcers and erosive oesophagities, and for reducing gastric acid hyper secration in
patients with zollinger-ellison syndrome.

Indications
Duodenal and gastric ulcers, reflux or ulcerative oesophagitis. Zollinger-Ellison syndrome. NSAID-induced ulcers.

Dosage
Gastic ulcer; 20 mg once daily for 8 weeks, in severe cascs increase to 40 mg once daily.
Reflux oesophagitis; 20 mg once daily for 4 weeks, refractory cases 40 mg once daily.
Duodenal ulcer; 20 mg once daily for 4 weeks.
Zollinger-ellison syndrome; 60 mg once. Maintenance therapy 20-120 mg adjusted to response, doses over 80 mg daily should be divided in 2 doses.

Contraindications
Hypersensitivity, Neonates

Warnings and Precautions
Exclude the presence of gastricmalignancy. Impaired renal & hepatic functions.
Pediatric: not recommended.
Pregnancy: Safety not established.
Lactation: safety not established.
Elderly: No special Problem.

Side effects and adverse reactions
Skin rash, nausea, headache, diarrhoea, constipation and flatulence. Increased risk of enteric infection due to reduced acid secration.

Drug Interactions
Prolongs elimination of diazepam, warfarin, phenytoin, aminophylline, antitrypsin.

Pack
10 or 7 capsules packed in a Alu/Alu, such 1 or 2 blister packed in a unit printed duplex board carton. Such cartons packed in export worthy shipper corrugated box or Jar pack of 1000 capsules.

Storage
Store in a cool, dry and dark place. Protect from light.
Keep out of reach children.

Nafdac Reg. No.:A4-4652

Manufactured in India by
GLOBELA PHARMA PVT. LTD
Plot No. 357,
G.I.D.C, Sachin,
Surat 394 230,
Gujarat, India

Sole Agent
Uche St Company (Nig.) Ltd.
Pharmacuetical Divison
No .9, Ekwulummiri Street,
Iyiowa Odekpe Ogbaru,
Anambra State, Nigeria.

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