KUCAM PIROXICAM CAPSULES 20mg
Composition, Introduction, Indications, Dosage and administration, Absorption and excretion, Contraindications, Warning, Side effects, Presentation, NAFDAC Reg. No., Manufacturer and Marketer of Kucam Capsule Medicine for Arthritis.
Each capsule contains:
Piroxicam is a non-steroidal anti-inflammatory drug with best anti-arthritis activity. It inhibits the activity of prostaglandin synthetase enzyme, which is responsible for the biosynthesis of prostaglandins, the known mediators of inflammation. Piroxicam also inhibits collagen induced platelet aggregation.
Piroxicam is indicated for the acute and long term treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute musculoskeletal disorders, acute gout, postoperative and post-traumatic pain and primary dysmenorrhoea.
DOSAGE AND ADMINISTRATION
Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis: 20mg daily as a single dose.
Acute musculoskeltal disorders: 40mg daily in single or divided doses for first 2 days, 20mg daily for the remaining 7 to 14 days.
Primary dysmenorrheal: 40mg daily for first 2 days, 20mg daily for 2 – 3 days thereafter.
ABSORPTION AND EXCRETION
Piroxicam is well absorbed from the gastro-intestinal tract, it is metabolized in the liver by hydroxylation and conjugation with glucuronic acid and excreted predominantly in the urine with smaller amounts in the faeces, less than 5% of the dose is excreted unchanged.
Piroxicam should be used with caution in patients with impaired renal function, in patients with cardiovascular disorders and in patients known to be hypersensitive to aspirin.
Safety during pregnancy and lactation has not been established, dosage recommendations and indications for use in children under 12 years have not been established.
Gastro-intestinal disturbances are the most common adverse effect. Peptic ulceration and gastro-intestinal bleeding have been rarely reported. Other side effects which have been reported include headache, dizziness, blurred vision, tinnitus, rashes, pruritus and oedema.
Pack of 10 blisters strips of 10 capsules, 1 blister strip of 10 capsules.
KEEP ALL MEDICINES OUT OF REACH OF CHILDREN
NAFDAC REG. NO.: B4-5956
For the use only of Medical Profession, Hospital or a Laboratory.
SHANDONG XIER KANGTAI PHARM CO., LTD.
Private Economy Garden, Xinyan Town,
Yanzhou City, Shandong, China.
Pharmamax Nigeria Limited
(A member of KCH Group)
T1, Crown Centre, Crown Estate Lekki, Lagos-Nigeria