Magnavit Multivitamin and Minerals Capsules

MAGNAVIT™ (Multivitamin & Minerals Capsules)



Each soft gelatin capsule contains:

Vitamin A (Palmitate) USP 2000IU

Vitamin B1 BP 1mg

Vitamin B2 BP 1mg

Vitamin B6 BP 1.34mg

Vitamin B12 BP 1mcg

Vitamin D3 BP 2001U

Calcium D Pantothenate USP 1mg

Nicotinamide BP 15mg

Calcium (as Dicalcium Phosphate) BP 190mg

Phosphorus (as Dicalcium phosphate) BP 140mg

Magnesium (as Magnesium sulphate) BP 1mg

Iron (as Ferrous sulphate) BP 5mg

Manganese (as Manganese sulphate) BP 0.01mg

Copper (as Copper sulphate) BP 0.01mg

Zinc (as Zinc sulphate) BP 0.15mg

Potassium (as Potassium iodide) BP 1mg

Iodine (as Potassium Iodide) BP 0.0015mg.


Arachis Oil BP

Hydrogenated Castor Oil BP

Gelatin BP

Glycerin BP

Methyl Paraben BP

Propyl Paraben BP

Butylated Hydroxyanisole BP

Purified water BP.


Pharmacological category

Magnavit is a nutritional supplement containing minerals, multivitamins and trace elements.


Pharmacological action

Magnavit contains vitamins and dietary minerals which are fundamentally involved in vital metabolic processes, where they serve as oxidising or reducing agents and as co-factors in various enzyme systems. These essential micronutrients are so closely interrelated that the lack of any one of them may affect the body requirements of others.

Vitamin A is essential for the production and regeneration of visual purple of retina, for maintenance of integrity of epithelial tissue.

Vitamins B-complex usually function as co enzyme in carbohydrate, protein and amino acid metabolism, DNA synthesis, maturation of RBCs, nerve cell function.

Vitamin D3 is essential for the growth of bone through regulation of calcium absorption Calcium D Pantothenate is a component of coenzyme A which is essential in the metabolism of carbohydrate, fat and protein.

Nicotinamide plays a vital role in metabolism of proteins essential for tissue respiration. Calcium is used as a dietary supplement. It is essential for the maintenance of normal bone and calcium salts, may be indicated in the treatment of bone disorder.

Phosphorus plays a dynamic role in energy metabolism, modifies the tissue concentrations of calcium ions and plays a major role in renal excretion of hydrogen ions. Certain peptidases and phosphatases require Magnesium for maximal activity. Iron is required as a component of haemoglobin in Red Blood Cells.

Manganese is an essential trace element activates numerous enzyme systems including those involved with glucose metabolism, energy production. It is a major constituent of several metalloenzymes, hormones and proteins of humans.

Copper is required in the formation of hemoglobin, red blood cells as well as bones, while it helps in the formation of elastin and collagen necessary for wound healing.

Zinc is necessary for a healthy immune system, needed for cell division, and is needed by the tissue of the hair, nails and skin to be in top form. Zinc is further used in the growth and maintenance of muscles.

Potassium is essential for many metabolic and physiological processes including nerve conduction, muscle contraction and acid-base regulation.

Iodine is used in the production of hormones (such as thyroxine, thyroxin) by the thyroid gland, which in turn regulates the conversion of fat to energy, stabilizing our body weights well as controlling our cholesterol levels.



Vitamin A is a fat soluble vitamin and is readily absorbed from the normal gastrointestinal tract. Plasma concentrations reach a peak level within 3 to 5 hours. Beta-carotene is converted to retinal, which is mostly reduced to retinol and conjugated with glucuronic acid and excreted in the urine and feces. Some retinol is esterified mainly to retinyl palmitate. Normal plasma concentration is approximately 1.4µmol/L (130 units/100 mL). Retinyl palmitate and small amounts of retinol and retinal are stored in the liver.

Body stores of vitamin A are normally sufficient to meet the body’s needs for up to 2 years. The lipophilic nature of vitamin D explains its adipose tissue distribution and its slow turnover in the body (half-life approximately 2 months). Its main transported metabolite, 25-hydroxyvitamin D(3) [25 (OH) D (3)], shows a half-life of approximately 15 days and circulates at a concentration of 25-200 nmol/L, whereas the hormone 1alpha,
25(OH)(2)D(3) has a half-life of approximately 15 h.

Diphasic calcium dissolves in the presence of HCI in stomach and then it is absorbed. Oral absorption of iron salts is complex and is determined by a variety of factors, including diet, iron stores present, degree of erythropoiesis, and dose. Iron is thought to be absorbed throughout the GI tract, but is most absorbed in the duodenum and proximal jejunum. Food in the GI tract may reduce the amount absorbed. After absorption, the ferrous iron is immediately bound to transferrin, and is transported to the bone marrow and eventually incorporated into hemoglobin.


Therapeutic indications

Magnavit contains adequate concentration of all essential vitamins and minerals to meet usual and increased demands of the body for periods of active growth, convalescence, pregnancy, lactation, nutritional deficiency states and stressful conditions. Thus, Magnavit provides vitamins and minerals needed for blood and body building.



Magnavit is contraindicated in conditions of haemochromatosis and haemosiderosis.


Dosage and directions for use

Oral route. Unless otherwise prescribed by the medical practitioner, one capsule per day to be taken at the main meal.



The use of Nicotinamide containing preparations in patients with gastritis, peptic ulcers or asthma should be undertaken carefully. Iron deficiency anaemia may be a manifestation of chronic disease which should be detected and treated if possible.


Adverse reactions

Allergic reactions viz skin rashes and gastrointestinal disturbances such as nausea, vomiting, diarrhoea or constipation may occur. A generalized flushing and a feeling of warmth has been reported following nicotinamide therapy.

Vitamin D: Should not be administered to patients with hypercalcaemia, and be given with caution to infants, as they may have increased sensitivity to its effects.


Warnings and precautions for use in special populations

Caution: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately. The use of Nicotinamide containing preparations in patients with gastritis, peptic ulcers or asthma should be undertaken carefully. Iron deficiency anaemia may be a manifestation of chronic disease which should be detected and treated if possible. Excessive doses of Vitamin A should be avoided in pregnancy because of potential teratogenic effects. Lactating women should not take vitamin D if possible, as this may lead to the development of hypercalcaemia in the infant.


Usage in pregnancy and lactation

It can be given during pregnancy and lactation, however in case of anemia, therapeutic dose of iron should be given along with folic acid.


Effects on ability to drive and operate machinery

Not applicable.


Drugs interactions

Oral iron preparations interfere with absorption of oral tetracyclines, these products should be taken within two hours of each other. Mineral reduces absorption of fat soluble Vitamins such as A and D.

Vitamin A: Absorption of vitamin A from the gastro-intestinal tract may be reduced by the presence of neomycin, cholestyramine, or liquid paraffin; absorption may also be impaired in cholestatic jaundice and fat-malabsorption conditions.

Vitamin B6: Reduces the effects of levodopa.

The effects of Vitamin D may be reduced in patients taking barbiturates or anticonvulsants.


Symptoms of over dosage and its treatment

Massive overdosage may cause gastrointestinal upsets which will disappear on withdrawal of the product. Overdosage over long periods with Vitamin A can lead to Hypervitaminosis A characterised by fatigue, irritability, anorexia and weight loss, vomiting and gastro-intestinal disturbances, low-grade fever, skin changes, hair loss, dry hair, cracked and bleeding lips, anaemia, headache, hypercalcaemia, pains in bones and joints. Symptoms of chronic toxicity in children may include raised intercranial pressure, and papilloedema mimicking brain tumours, tinnitus, visual disturbances and painful swelling over the long bones. Symptoms usually clear on withdrawal of Vitamin A but in children premature closure of the epiphyses of the long bones may result in arrested growth. Acute Vitamin A intoxication may occur with very high doses and is characterised by sedation, dizziness, nausea and vomiting, erythema, pruritis and desquamation. Overdosage with Vitamin B12 results in a bright yellow discoloration of the urine. Long-term overdosage with Vitamin B6 is associated with the development of severe peripheral neuropathies.

Vitamin D: Excessive intake of Vitamin D leads to the development of hyper-calcaemia which is characterised by anorexia, nausea, vomiting, constipation, abdominal pain, muscle weakness, mental disturbances, polydipsia, polyuria, bone pain, nephrocalcinosis, renal calculi, and in severe cases cardiac arrhythmias and coma.

Treatment is symptomatic and supportive.


Storage Condition

Do not store above 30°C. Protect from sunlight. Keep out of reach of children.



Magnavit Blister Pack of 2 x 15 capsules.


Publication Date: 29/7/2015

NAFDAC Reg No.: 04-3255


Manufactured for


96, Maker Chambers VI, Nariman Point, Mumbai-India.


Manufactured by


86 – A, L. B. Shastri Marg, Mulund,

Mumbai 400080, Maharashtra, India.

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