MF – 20 Piroxicam Capsules 20mg
Composition, Properties, Onset of action, Duration of action, Adverse effects, Contraindications, Specific precaution, Interactions, Indications, Dosage, Storage, Presentation, NAFDAC Reg. No. Agent and Manufacturer and of MF-20 Piroxicam Capsules Medicine for Arthritis.
Each capsule contains:
Piroxicam USP 20mg
Capsule shell contains approved colours
MF-20 is an effective anti-inflammatory, analgesic and antipyretic drug.
MF-20 is completely absorbed after oral administration. It undergoes enterohepatic cycling and is extensively bound to plasma proteins.
Onset of action
Analgesic action 1 hour, antirheumatic action 7-12 days
Duration of action
Nausea, heart burn, vomiting, epigastric distress, tinnitus, skin rash, oedema.
History of recurrent ulcer, NSAID induced allergy, hypersensitivity, bronchial asthma.
Severe impairment of hepatic or renal function. Hypertension, surgery haemorrhagic disorders on prolonged used. Contraindicated in pregnancy. Use with caution in children.
Antocoagulants: May prolong prothrombin time in coagulation.
B-Blockers: Antihypertensive effect may be increased.
Cyclosporine: Nephrotoxicity of both agents may be increased.
Lithium: Serum Lithium levels increased resulting in increased pharmacologic and toxic effects.
Methotrexate: Risk of methotrexate toxicity (stomatitis, bone marrow suppression nephrotoxicity) increased.
Probenecid: May increase the concentration and toxicity of MF-20
Aspirin: Displaces MF-20 from serum binding sites resulting in increased incidence of gastric irritations effects.
Rheumatoid arthritis, Oesteoarthritis, ankylosing spondylitis, Acute musculoskeletal disorders. Acute gout, post-operative and post-traumatic pain. Primary dysmenorrheal.
Adults: 1 Capsule daily as a single dose.
Musculo-skeletal disorders: Initially 2 capsules daily for 2 days then 1 capsule daily for 7 to 14 days.
Gout: Initially 2 capsules as a single dose then 2 capsules daily in single or divided doses for next 4-6 days.
Post-operative and post-traumatic pain: 2 capsules daily in single or divided doses for first two days or as directed by the Physician.
Children: Not recommended.
Store in a cool, dry place.
Protect from light.
Keep all medicines away from children.
Blister of 10 capsules
Carton of 1 x 10 capsules
Carton of 10 x 10 capsules.
NAFDAC Reg. No.: 04-1889
Ningbo Dahongying Pharmaceutical Co., Ltd.
No. 396 Mingzhu Road, Hi-tech Park, Nongbo, China.
Embassy Pharmaceutical and Chemicals Ltd.