Nestro Trypsin Chymotrypsin Tablets

NESTRO
Trypsin-Chymotrypsin 50,000 armour units of enzymatic activity

 

Each enteric coated tablets contains:

50,000 armour units of enzymatic activity.

* Supplied by a purified concentrate which has specific trypsin and chymotrypsin, activity in a ratio of approximately six to one.

Proteolytic enzymes speed the healing of damaged tissue and promote a Complication free recovery. Trypsin & chymotrypsin are released and absorbed in the small intestine when given in enteric coated form. This mode of administration protects the enzymes from the destructive activity of the acid pepsin in the stomach and promotes intestinal absorption.

 

Pharmacokinetics

On being absorbed, the enzymes are taken up by the circulating enzymes inhibitors (alpha 1 antitrypsin and alpha 2 macroglobulin), levels of which show a steep rise following injury and tissue destructive disease. This rise in inhibitor levels is responsible for the post operative fibrinolytic shut down and maintenance of inflammatory oedema which delay healing.

By bringing about on earlier reversal of the rising plasmin inhibitor levels these facilitate the action of plasmin which is necessary to open up blocked microcirculation, resolve oedema and initiate healing.

The inference is that the fibrin blocked microcirculation could be cleared earlier by the administration of the enzymes, and hence the inflammation resolve quicker, and healing commences at an early stage.

 

Indication

Resolution of acute inflammatory oedema associated with accidental and surgical trauma, episitomies, in pelvic inflammatory disorders, intervertebral disc herniation (sciatica), thrombophlebitis, vasectomies and reduction in viscosity of mucus and sputum associated with bronchitis, rhinitis and sinusitis, dental extraction and surgery, enhancement of antibiotic concentration at the infection and prevention of formation of adhesions.

 

Contraindication

Hypersensitivity.

 

Dosage

1-2 lacs Armour units (AU) 4 times daily, 1/2 hour before meals.

 

Storage

Store in a cool, dry & dark place.

KEEP MEDICINE OUT OF REACH OF CHILDREN

 

Presentation

Available in a 3 X 10 Tablets.

 

NAFDAC Reg. No.: A4-9473

 

Manufactured in India by

JAY FORMULATIONS LTD.

1301 & U-1, G.I.D.C. Kerala (Bavla),

Dist : Ahmedabad-382220, Gujarat, INDIA

 

Exported by

NEST LIFESCIENCE Pvt. Ltd.

nestlifescience@yahoo.in